Rat G Protein-coupled Receptor Kinase 6, GRK6 ELISA Kit

SKU: E1969Ra

Size:96 Tests-1 Kit

Background:Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro) (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:GRK6

Reactivity:Rat

Assay type:Sandwich

Sensitivity:9.69ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:G protein-coupled receptor kinase 6

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P97711

MASS(Da):65,963

GeneID:59076

Synonyms:G protein-coupled receptor kinase 6;G protein-coupled receptor kinase GRK6;Gprk6;GRK6

Gene names:Grk6

Standard solution:4800ng/L