Rat Fibronectin, FN ELISA Kit

SKU: E0633Ra

Size:96 Tests-1 Kit

Background:Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (By similarity). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). Binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Research_area:Cardiovascular; Signal Transduction; Stem Cells; Cancer; Developmental Biology

Applications:ELISA

Target_protein:FN

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.043ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Fibronectin

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P04937

MASS(Da):272,511

GeneID:25661

Synonyms:Anastellin];FIBNEC;Fibronectin;FN;fn-1

Gene names:Fn1

Standard solution:48ng/ml