Rat Cytochrome P450 19A1, CYP19A1 ELISA Kit

SKU: E0912Ra

Size:96 Tests-1 Kit

Background:Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1, a member of the cytochrome P450 superfamily (EC 1.14.14.1), which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The enzyme aromatase can be found in many tissues including gonads (granulosa cells), brain, adipose tissue, placenta, blood vessels, skin, and bone, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer.[citation needed] It is an important factor in sexual development.

Research_area:Others

Applications:ELISA

Target_protein:CYP19A1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.03ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Cytochrome P450 19A1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P22443

MASS(Da):58,412

GeneID:25147

Synonyms:Aromatase;Cyp19;Cyp19a;CYP19A1;CYPXIX;Cytochrome P450 19A1;Cytochrome P-450AROM;Estrogen Synthase;p450arom;

Gene names:Cyp19a1

Standard solution:32ng/ml