Rat Chordin ELISA Kit PicoKine®

SKU: EK2086

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: Chrd

Specificity: Natural and recombinant rat Chordin

Background: Chordin is a bone morphogenetic protein antagonist composed of four small cysteine-rich domains, whose function is not known. In humans, the chordin peptide is encoded by the CHRD gene. It is mapped to 11q23. It dorsalizes the developing embryo by binding ventralizing TGFβ proteins such as bone morphogenetic proteins. It may also play a role in organogenesis. In mice, Chordin is expressed in the node but not in the anterior visceral endoderm. It has been found to be required for forebrain development. In developing mice that are deficient in both chordin and noggin, the head is nearly absent. This is significant because when only noggin is deficient there are mild defects but the head still forms. Chordin is also involved in avian gastrulation. It is expressed in the anterior cells of Koller's sickle, which form the anterior cells of the primitive streak, a key structure through which gastrulation occurs.

Immunogen: Expression system for standard: NS0; Immunogen sequence: T27-S948

Clonality:

Contents:

Purification:

Reconstitution:

Reference:

Uniprot ID: Q63148

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 117275

Protein Name: Chordin

Gene Full Name: chordin

Synonyms: Chordin; CHRD; UNQ217/PRO243