Rat Calcium Sensing Receptor,CASR ELISA KIT

SKU: E1497Ra

Size:96 Tests-1 Kit

Background:G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (PubMed:7816802). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as Trp or Phe, act concertedly with divalent cations, such as calcium or magnesium, to achieve full receptor activation (By similarity). {ECO:0000250|UniProtKB:P41180, ECO:0000250|UniProtKB:Q9QY96}.

Research_area:

Applications:ELISA

Target_protein:Casr

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.017ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Calcium Sensing Receptor

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P48442

MASS(Da):120868

GeneID:24247

Synonyms:Casr Gprc2a Pcar1

Gene names:Casr

Standard solution:16ng/ml