Rat Calcium;Calmodulin-Dependent Protein Kinase 2 Alpha,CAMK2A ELISA KIT

SKU: E2556Ra

Size:96 Tests-1 Kit

Background:Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (PubMed:15312654). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (By similarity). Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity (By similarity). {ECO:0000250|UniProtKB:P11798, ECO:0000250|UniProtKB:Q9UQM7, ECO:0000269|PubMed:15312654}.

Research_area:

Applications:ELISA

Target_protein:Camk2a

Reactivity:Rat

Assay type:Sandwich

Sensitivity:3.32ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:CalciumCalmodulin-Dependent Protein Kinase 2 Alpha

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11275

MASS(Da):54115

GeneID:25400

Synonyms:Camk2a

Gene names:Camk2a

Standard solution:1600ng/L