Rat beta-site APP-cleaving enzyme 2;Beta-secretase 2,BACE2 ELISA KIT

SKU: E0099Ra

Size:96 Tests-1 Kit

Background:Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672 (By similarity). Responsible also for the proteolytic processing of CLTRN in pancreatic beta cells (By similarity). {ECO:0000250|UniProtKB:Q9Y5Z0}.

Research_area:

Applications:ELISA

Target_protein:Bace2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:beta-site APP-cleaving enzyme 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6IE75

MASS(Da):55858

GeneID:288227

Synonyms:Bace2

Gene names:Bace2

Standard solution:24ng/ml