Rat Alpha-1-macroglobulin, ALPHA-1-M ELISA Kit

SKU: E1115Ra

Size:96 Tests-1 Kit

Background:Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a Peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:A1M

Reactivity:Rat

Assay type:Sandwich

Sensitivity:9.32ng/ml

Detection range:20-4000ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Alpha-1-Macroglobulin

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q63041

MASS(Da):167,125

GeneID:252922

Synonyms:A 1M;A1M;Alpha-1-M;Alpha-1-macroglobulin;Alpha-1-macroglobulin 165 kDa subunit;Alpha-1-macroglobulin 45 kDa subunit

Gene names:A1M

Standard solution:4800ng/ml