RANBP10 antibody , Cat. # FNab07101

SKU: FNab07101

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as a guanine nucleotide exchange factor(GEF) for RAN GTPase(By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function(By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway.

Immunogen:RAN binding protein 10

Synonyms:KIAA1464

Observed MW:67-70 kDa

Uniprot ID:Q6VN20

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID:57610

Research Area:Metabolism