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Gene Bio Systems

RAMP1 Antibody - Cat. #: CSB-PA995687

RAMP1 Antibody - Cat. #: CSB-PA995687

SKU:CSB-PA995687

Regular price £292.00 GBP
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Size :50ul

Clone Number:

Aliases:Calcitonin receptor like receptor activity modifying protein 1 antibody; Calcitonin-receptor-like receptor activity-modifying protein 1 antibody; CRLR activity modifying protein 1 antibody; CRLR activity-modifying protein 1 antibody; Ramp1 antibody; RAMP1_HUMAN antibody; receptor (calcitonin) activity modifying protein 1 antibody; Receptor (G protein coupled) activity modifying protein 1 antibody; Receptor activity modifying protein 1 [Precursor] antibody; Receptor activity-modifying protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O60894

Immunogen:Fusion protein of Human RAMP1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:10-1:50

Background:The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAMP1

Research Areas:Neuroscience;Signal transduction

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