RAB31 Antibody - Cat. #: CSB-PA614438ESR2HU

SKU: CSB-PA614438ESR2HU

Size :50ul

Clone Number:

Aliases:Rab 22B antibody; RAB 31 antibody; Rab22B antibody; Rab31 antibody; RAB31 member RAS oncogene family antibody; RAB31_HUMAN antibody; Ras related protein Rab 31 antibody; Ras related protein Rab31 antibody; Ras-related protein Rab-22B antibody; Ras-related protein Rab-31 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13636

Immunogen:Recombinant Human Ras-related protein Rab-31 protein (1-194AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAB31

Research Areas:Signal transduction