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Gene Bio Systems

RAB17 Antibody - Cat. #: CSB-PA863944ESR2HU

RAB17 Antibody - Cat. #: CSB-PA863944ESR2HU

CSB-PA863944ESR2HU

£287.00 GBP
£287.00 GBP
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Size :50ul

Clone Number:

Aliases:AW413472 antibody; FLJ12538 antibody; OTTHUMP00000164417 antibody; OTTHUMP00000202805 antibody; Rab 17 antibody; Rab17 antibody; RAB17 member RAS oncogene family antibody; RAB17_HUMAN antibody; Ras related protein Rab 17 antibody; Ras related protein Rab17 antibody; Ras-related protein Rab-17 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H0T7

Immunogen:Recombinant Human Ras-related protein Rab-17 protein (1-212AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAB17

Research Areas:Signal transduction

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