PVRL1 Antibody - Cat. #: CSB-PA139246

SKU: CSB-PA139246

Size :50ul

Clone Number:

Aliases:CD111 antibody; CD111 antigen antibody; CLPED1 antibody; ectodermal dysplasia 4 (Margarita Island type) antibody; ED4 antibody; Herpes virus entry mediator C antibody; Herpesvirus entry mediator C antibody; Herpesvirus Ig like receptor antibody; Herpesvirus Ig-like receptor antibody; HIgR antibody; HveC antibody; MGC142031 antibody; Nectin 1 antibody; Nectin-1 antibody; OFC7 antibody; OROFACIAL CLEFT 7 antibody; OTTHUMP00000232093 antibody; OTTHUMP00000232094 antibody; OTTHUMP00000232095 antibody; Poliovirus receptor related protein 1 antibody; poliovirus receptor-like 1 antibody; Poliovirus receptor-related protein 1 antibody; PRR antibody; PRR1 antibody; PVRL 1 antibody; PVRL1 antibody; PVRL1_HUMAN antibody; PVRR antibody; PVRR1 antibody; SK-12 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15223

Immunogen:Synthetic peptide of Human PVRL1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:500-1:5000, WB:1:200-1:1000

Background:This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NECTIN1

Research Areas:Neuroscience;Microbiology