Purified Anti-Mouse/Human CD11b Antibody[M1/70]

SKU: GBS-F1081A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD11b

Target Synonym:CD11 antigen-like family member B;CD11b;CR-3 alpha chain;Integrin alpha-M;Itgam;Leukocyte adhesion receptor MO1

Research Areas:Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Neuroscience;Neuroscience Cell Markers

Conjugation:Unconjugated

Host:Rat

Species reactivity:Human;Mouse

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Rat IgG2b, κ

Clonality:Monoclonal

Clone NO.:M1/70

UNIProt ID:P05555;P11215;

Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:3684