Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7]

SKU: GBS-F1035A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD120b/TNFR2

Target Synonym:CD120b;TNF-R2;TNF-RII;TNFR-II;Tnfrsf1b;Tumor necrosis factor receptor 2;Tumor necrosis factor receptor superfamily member 1B;p75;p80 TNF-alpha receptor

Research Areas:Immunology;Innate Immunity

Conjugation:Unconjugated

Host:Armenian Hamster

Species reactivity:Mouse

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Armenian Hamster IgG

Clonality:Monoclonal

Clone NO.:TR75-54.7

UNIProt ID:P25119

Background:CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:

Dilution:

GeneID:21938