Purified Anti-Human CD42b Antibody[HIP1]

SKU: GBS-F1327A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD42b

Target Synonym:DBPLT;GP1BA;BDPLT1;BDPLT3;BSS;CD42B;CD42b-alpha;DBPLT3;GP1B;GPIbA;GPIbalpha;VWDP;Carbohydrate-Rich Portion of Platelet Membrane Glycoprotein Ib Alpha Polypeptide;Antigen CD42b alpha;CD 42b;CD42b alpha;CD42b antigen;GLYCOCALICIN;Glycoprotein Ib (platelet) alpha polypeptide;Glycoprotein Ibalpha;GP Ib alpha;GPIb alpha;MGC34595;Platelet glycoprotein Ib alpha chain;Platelet glycoprotein Ib alpha polypeptide;Platelet membrane glycoprotein 1b alpha subunit

Research Areas:

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1,κ

Clonality:Monoclonal

Clone NO.:HIP1

UNIProt ID:P07359

Background:Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD42b protein

Buffer:PBS, pH 7.2. Contains 0.05% proclin 300.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID: