ptxA Antibody - Cat. #: CSB-PA356423LA01Bua

SKU: CSB-PA356423LA01Bua

Size :50ug

Clone Number:

Aliases:ptxA antibody; BP3783 antibody; Pertussis toxin subunit 1 antibody; PTX S1 antibody; Islet-activating protein S1 antibody; IAP S1 antibody; NAD-dependent ADP-ribosyltransferase antibody; EC 2.4.2.- antibody

Product Type:Polyclonal Antibody

Immunogen Species:Bordetella pertussis

UniProt ID:P04977

Immunogen:Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269AA)

Raised in:Rabbit

Species Reactivity:Bordetella pertussis

Tested Applications:ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background:S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ptxA

Research Areas:Others