PTPA Antibody, FITC conjugated - Cat. #: CSB-PA620876LC01HU

SKU: CSB-PA620876LC01HU

Size :50ug

Clone Number:

Aliases:subunit B'' antibody; KIAA0044 antibody; MGC2184 antibody; Phosphotyrosyl phosphatase activator antibody; PP2A antibody; PP2A phosphatase activator antibody; PP2A subunit B' antibody; PP2A subunit B' isoform PR53 antibody; PP2A subunit B' PR53 isoform antibody; PPP2R4 antibody; PR53 antibody; PR53 isoform antibody; Protein phosphatase 2, regulatory subunit B-prime antibody; Protein phosphatase 2A activator regulatory subunit 4 antibody; Protein phosphatase 2A regulatory subunit B' (PR 53) antibody; PTPA antibody; PTPA_HUMAN antibody; Serine/threonine protein phosphatase 2A regulatory subunit B' antibody; Serine/threonine-protein phosphatase 2A activator antibody; Serine/threonine-protein phosphatase 2A regulatory subunit 4 antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15257

Immunogen:Recombinant Human Serine/threonine-protein phosphatase 2A activator protein (1-250AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTPA

Research Areas:Signal transduction