PTN Antibody - Cat. #: CSB-PA286956

SKU: CSB-PA286956

Size :50ul

Clone Number:

Aliases:HARP antibody; HB-GAM antibody; HBBM antibody; HBGAM antibody; HBGF-8 antibody; HBGF8 antibody; HBNF antibody; HBNF-1 antibody; HBNF1 antibody; heparin affin regulatory protein antibody; Heparin binding growth associated molecule antibody; Heparin binding growth factor 8 antibody; Heparin binding neurite outgrowth promoting factor 1 antibody; Heparin-binding brain mitogen antibody; Heparin-binding growth factor 8 antibody; Heparin-binding growth-associated molecule antibody; heparin-binding neurite outgrowth promoting factor antibody; Heparin-binding neurite outgrowth-promoting factor 1 antibody; NEGF1 antibody; Neurite growth promoting factor 1 antibody; Neurite outgrowth-promoting factor; heparin-binding antibody; OSF-1 antibody; OSF1 antibody; Osteoblast-specific factor 1 antibody; pleiotrophin (heparin binding growth factor 8; neurite growth-promoting factor 1) antibody; Pleiotrophin antibody; PTN antibody; PTN_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P21246

Immunogen:Synthetic peptide of Human PTN

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:Pleiotrophin (PTN) also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM) is a protein that in humans is encoded by the PTNgene. Pleiotrophin is an 18-kDa growth factor that has a high affinity for heparin. It is structurally related to midkine and retinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTN

Research Areas:Neuroscience?Cancer;Immunology;Signal transduction