PRPF18 rabbit pAb

SKU: ES3263

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;IHC

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from human PRPF18. AA range:182-231

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):40kD

Human_gene_id:8559

Human_swiss_prot_no:Q99633

Subcellular_location:Nucleus speckle . Colocalizes with spliceosomal snRNPs. .

Other_name:PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18

Background:Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008],