Prnp Antibody - Cat. #: CSB-PA018739LA01RA

SKU: CSB-PA018739LA01RA

Size :50ug

Clone Number:

Aliases:Prnp antibody; Prn antibody; Prp antibody; Major prion protein antibody; PrP antibody; CD antigen CD230 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Rattus norvegicus (Rat)

UniProt ID:P13852

Immunogen:Recombinant Rat Major prion protein (29-231AA)

Raised in:Rabbit

Species Reactivity:Rat

Tested Applications:ELISA

Background:Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Prnp

Research Areas:Others