PRKG2 Antibody - Cat. #: CSB-PA041842

SKU: CSB-PA041842

Size :50ul

Clone Number:

Aliases:CGK 2 antibody; cGK2 antibody; cGKII antibody; cGMP dependent protein kinase 2 antibody; cGMP-dependent protein kinase 2 antibody; cGMP-dependent protein kinase II antibody; KGP2_HUMAN antibody; PRKG 2 antibody; PRKG2 antibody; PRKGR2 antibody; Protein kinase; cGMP dependent; type II antibody; Type II cGMP dependent protein kinase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13237

Immunogen:Synthetic peptide of Human PRKG2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:15-1:50

Background:cGKII (cGMP-dependent protein kinase type II) is a major receptor of intracellular cGMP and mediates a plethora of physiological responses. cGKII contains a conserved leucine zipper motif at the amino-terminus. It is expressed in small intestine, colon, prostate, and human brain tissues, and the cGKII gene maps to chromosome 4q13.1-q21.1. cGKII has been shown to regulate the ion transport system in the intestine. Myristoylation of the penultimate glycine in cGKII appears to be essential for directing cGKII to the membrane, since cGKII is devoid of any hydrophobic transmembrane domains. The translocation of cGKII from the cytosol to the membrane allows it to function properly in regulating intestinal ion transport.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PRKG2

Research Areas:Signal transduction