PRKAB2 Antibody - Cat. #: CSB-PA527326ESR1HU

SKU: CSB-PA527326ESR1HU

Size :50ul

Clone Number:

Aliases:5' AMP activated protein kinase beta 2 subunit antibody; 5' AMP activated protein kinase subunit beta 2 antibody; 5''-AMP-activated protein kinase subunit beta-2 antibody; AAKB2_HUMAN antibody; AMP activated protein kinase beta 2 non catalytic subunit antibody; AMPK beta 2 antibody; AMPK beta 2 chain antibody; AMPK subunit beta 2 antibody; AMPK subunit beta-2 antibody; MGC61468 antibody; PRKAB 2 antibody; Prkab2 antibody; Protein kinase AMP activated beta 2 non catalytic subunit antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43741

Immunogen:Recombinant Human 5\\\'-AMP-activated protein kinase subunit beta-2 protein (1-272AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:2000

Background:Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PRKAB2

Research Areas:Cancer; Cardiovascular; Metabolism; Signal transduction