PPR1A Polyclonal Antibody

SKU: BT-AP13271

Size:100μL

Background:Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.,PTM:Phosphorylation of Thr-35 is required for activity.,Belongs to the protein phosphatase inhibitor 1 family.,subunit:Interacts with PPP1R15A.,

Research_area:Metabolism; Signal transduction

Target_protein:PPP1R1A

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Protein phosphatase 1 regulatory subunit 1A

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q13522; Mouse: Q9ERT9; Rat: P19103

Synonyms:Protein phosphatase 1 regulatory subunit 1A ;Protein phosphatase inhibitor 1;I-1;IPP-1

GeneID:Human: 5502