PPP2R2B Antibody - Cat. #: CSB-PA168178

SKU: CSB-PA168178

Size :100ul

Clone Number:

Aliases:2ABB_HUMAN antibody; B55 beta antibody; Beta isoform of regulatory subunit B55 protein phosphatase 2 antibody; MGC24888 antibody; PP2A B55beta antibody; PP2A PR55B antibody; PP2A subunit B B beta isoform antibody; PP2A subunit B B55 beta isoform antibody; PP2A subunit B isoform B55 beta antibody; PP2A subunit B isoform B55-beta antibody; PP2A subunit B isoform beta antibody; PP2A subunit B isoform PR55 beta antibody; PP2A subunit B isoform PR55-beta antibody; PP2A subunit B isoform R2 beta antibody; PP2A subunit B isoform R2-beta antibody; PP2A subunit B PR55 beta isoform antibody; PP2A subunit B R2 beta isoform antibody; Ppp2r2b antibody; PR2AB beta antibody; PR2AB55 beta antibody; PR2APR55 beta antibody; PR52B antibody; PR55 beta antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B (PR 52) beta isoform antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B beta isoform antibody; Protein phosphatase 2 regulatory subunit B antibody; Protein phosphatase 2 regulatory subunit B beta isoform antibody; SCA 12 antibody; SCA12 antibody; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform antibody; Serine/threonine protein phosphatase 2A neuronal isoform antibody; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q00005

Immunogen:Synthesized peptide derived from internal of Human PPP2R2B.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity By similarity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance By similarity.

Mayer R.E., Biochemistry 30:3589-3597(1991) [PubMed: 1849734].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
Schmutz J., Nature 431:268-274(2004) [PubMed: 15372022].

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PPP2R2B

Research Areas:Neuroscience;Signal transduction