PPARGC1B Monoclonal Antibody

SKU: BT-MCA2023

Size:100μL

Background:The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Research_area:Cardiovascular, Epigenetics and nuclear signaling, Metabolism, Signal transduction

Target_protein:PPARGC1B

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:6C3F6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PPARGC1B

Immunogen:Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):113.2kDa

UniProt accession:Q86YN6

Synonyms:PERC, ERRL1, PGC1B, PGC-1(beta)

GeneID:133522