PPARG Monoclonal Antibody

SKU: BT-MCA4306

Size:100μL

Background:PPARG: peroxisome proliferator-activated receptor gamma. This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:PPARG

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:3A4A9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PPARG

Immunogen:Purified recombinant fragment of PPARG (aa170-270) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P37231

Synonyms:CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, PPARG

GeneID:5468