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GeneBio Systems

PPARD Monoclonal Antibody

PPARD Monoclonal Antibody

SKU:E-AB-22199

Regular price £425.00 GBP
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: PPAR Delta Mouse (1D7)

Target Synonym: FAAR;MGC3931;NR1C2;NUC1;NUCI;NUCII;Nuclear hormone receptor 1;Nuclear receptor subfamily 1 group C member 2;Peroxisome proliferative activated receptor delta;Peroxisome proliferator-activated receptor beta (PPAR-beta);Peroxisome proliferator-activated receptor beta;Peroxisome proliferator-activated receptor delta;PPAR beta;PPAR-beta;PPAR-delta;PPAR-;PPARB;ppard;PPARD

Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human;Mouse;Rat

Application: IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:1D7

UNIProt ID: Q03181

Accession:

Background: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein of PPAR Delta of PPAR Delta

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Protein A purification

Dilution: IHC 1:100-200

Calculated MW:

ObservedMW:

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