PPARA antibody , Cat. # FNab06663

SKU: FNab06663

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Immunogen:peroxisome proliferator-activated receptor alpha

Synonyms:hPPAR, NR1C1, PPAR, PPAR alpha, PPARA

Observed MW:52-55 kDa

Uniprot ID:Q07869

Reactivity:Human

Tested Application:ELISA, WB, IHC,IP

Recommended dilution:WB: 1:200-1:1000; IP: 1:200-1:1000 ; IHC: 1:50-1:200

Gene ID:5465

Research Area:Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience