PNPO Polyclonal Antibody

SKU: E-AB-19759

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PNPO

Target Synonym: EC 1.4.3.5;FLJ10535;PDXPO;PNPO;PNPO;Pyridoxal 5' phosphate synthase;pyridoxamine 5' phosphate oxidase;Pyridoxamine phosphate oxidase ;Pyridoxamine-phosphate oxidase;pyridoxine 5' phosphate oxidase;Pyridoxine-5'-phosphate oxidase

Research Areas: Metabolism;Neuroscience;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9NVS9

Accession:

Background: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human PNPO

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:20-1:100

Calculated MW: 30 kDa

ObservedMW: Refer to figures