PNN Antibody - Cat. #: CSB-PA184660

SKU: CSB-PA184660

Size :50ul

Clone Number:

Aliases:140 kDa nuclear and cell adhesion-related phosphoprotein antibody; Desmosome-associated protein antibody; Domain-rich serine protein antibody; DRS antibody; DRS protein antibody; DRSP antibody; Melanoma metastasis clone A protein antibody; MEMA antibody; Nuclear protein SDK3 antibody; Pinin antibody; PININ_HUMAN antibody; PNN antibody; SR like protein antibody; SR-like protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H307

Immunogen:Synthetic peptide of Human PNN

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a Moca type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PNN

Research Areas:Epigenetics and Nuclear Signaling;Cancer