PLAT Antibody - Cat. #: CSB-PA111403

SKU: CSB-PA111403

Size :50ul

Clone Number:

Aliases:Alteplase antibody; DKFZp686I03148 antibody; Plasminogen activator tissue antibody; Plasminogen activator tissue type antibody; PLAT antibody; Reteplase antibody; t PA antibody; T Plasminogen Activator antibody; t-PA antibody; T-plasminogen activator antibody; Tissue plasminogen activator (t PA) antibody; Tissue type plasminogen activator antibody; Tissue-type plasminogen activator chain B antibody; tPA antibody; TPA_HUMAN antibody; TPA1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P00750

Immunogen:Synthetic peptide of Human PLAT

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200

Background:This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLAT

Research Areas:Cancer?Cardiovascular?Cell biology;Metabolism