PKCdelta(Phospho-Tyr311) Rabbit Polyclonal Antibody

SKU: BT-AP04164

Size:100μL

Background:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters| a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth| apoptosis| and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Research_area:Cancer; Neuroscience; Signal transduction

Target_protein:PRKCD

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PKCdelta

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q05655; Mouse: P28867; Rat: P09215

Synonyms:PKCdelta ;Tyr311; Protein kinase C delta type; EC 2.7.11.13; Tyrosine-protein kinase PRKCD; EC 2.7.10.2; nPKC-delta

GeneID:Human: 5580; Mouse: 18753; Rat: 170538