PITRM1 Antibody - Cat. #: CSB-PA692283ESR2HU

SKU: CSB-PA692283ESR2HU

Size :50ul

Clone Number:

Aliases:hMP1 antibody; hPreP antibody; KIAA1104 antibody; Metalloprotease 1 antibody; MGC138192 antibody; MGC141929 antibody; mitochondrial antibody; MP1 antibody; Pitrilysin metallopeptidase 1 antibody; Pitrilysin metalloproteinase 1 antibody; PITRM 1 antibody; PITRM1 antibody; PreP antibody; PreP peptidasome antibody; PREP_HUMAN antibody; Presequence protease antibody; Presequence protease mitochondrial antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q5JRX3

Immunogen:Recombinant Human Presequence protease, mitochondrial protein (758-1037AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PITRM1

Research Areas:Cell biology