Phospho-TAL1 (Ser122) Antibody - Cat. #: CSB-PA117607

SKU: CSB-PA117607

Size :100ul

Clone Number:

Aliases:bHLHa17 antibody; Class A basic helix-loop-helix protein 17 antibody; OTTHUMP00000009563 antibody; OTTHUMP00000009564 antibody; SCL antibody; STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR antibody; Stem cell protein antibody; T cell acute lymphocytic leukemia 1 antibody; T cell acute lymphocytic leukemia 1 protein antibody; T cell acute lymphocytic leukemia 1 protein antibody; T cell leukemia/lymphoma 5 protein antibody; T-cell acute lymphocytic leukemia protein 1 antibody; T-cell leukemia/lymphoma protein 5 antibody; Tal 1 antibody; Tal 1 product antibody; TAL 1 protein antibody; TAL bHLH transcription factor 1 erythroid differentiation factor antibody; TAL-1 antibody; tal1 antibody; TAL1_HUMAN antibody; TCL 5 antibody; TCL5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P17542

Immunogen:Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1.

Raised in:Rabbit

Species Reactivity:Human, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).
Gregory S.G., Nature 441:315-321(2006).
Chen Q., J. Exp. Med. 172:1403-1408(1990).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TAL1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology?Developmental biology;Stem cells