Phospho-PLD1 (Thr147) Antibody - Cat. #: CSB-PA440926

SKU: CSB-PA440926

Size :100ul

Clone Number:

Aliases:Choline phosphatase 1 antibody; hPLD1 antibody; Phosphatidylcholine-hydrolyzing phospholipase D1 antibody; Phospholipase D1 antibody; PLD 1 antibody; PLD1 antibody; PLD1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13393

Immunogen:Peptide sequence around phosphorylation site of threonine 147(R-H-T(p)-F-R) derived from Human PLD1.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.

Hammond S.M., J. Biol. Chem. 272:3860-3868(1997) [PubMed: 9013646].
Steed P.M., FASEB J. 12:1309-1317(1998) [PubMed: 9761774].
Lopez I., J. Biol. Chem. 273:12846-12852(1998) [PubMed: 9582313].

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLD1

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction