Phospho-NOS3 (Ser1177) Antibody - Cat. #: CSB-PA279955

SKU: CSB-PA279955

Size :100ul

Clone Number:

Aliases:cNOS antibody; Constitutive NOS antibody; EC NOS antibody; EC-NOS antibody; ecNOS antibody; Endothelial nitric oxidase synthase antibody; Endothelial nitric oxide synthase antibody; Endothelial nitric oxide synthase 3 antibody; Endothelial NOS antibody; eNOS antibody; Nitric oxide synthase 3 (endothelial cell) antibody; Nitric oxide synthase 3 antibody; Nitric oxide synthase 3 endothelial cell antibody; Nitric oxide synthase endothelial antibody; Nitric oxide synthase; endothelial antibody; NOS 3 antibody; NOS III antibody; NOS type III antibody; NOS3 antibody; NOS3_HUMAN antibody; NOSIII antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P29474

Immunogen:Peptide sequence around phosphorylation site of serine 1177 (T-Q-S(p)-F-S) derived from Human eNOS.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:200

Background:

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Fulton, D. et al. (1999) Nature 399, 597-601.
Harris, M.B. et al. (2001) J. Biol. Chem. 276, 16587-16591.
Thomas, S.R. et al. (2002) J. Biol. Chem. 277, 6017-6024.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NOS3

Research Areas:Neuroscience?Cancer?Cardiovascular?Cell biology;Metabolism