Phospho-MED1 (Thr1457) Antibody - Cat. #: CSB-PA045259

SKU: CSB-PA045259

Size :100ul

Clone Number:

Aliases:Activator-recruited cofactor 205 kDa component antibody; ARC205 antibody; CRSP1 antibody; CRSP200 antibody; DRIP205 antibody; DRIP230 antibody; MED1 antibody; MED1_HUMAN antibody; Mediator complex subunit 1 antibody; Mediator of RNA polymerase II transcription subunit 1 antibody; p53 regulatory protein RB18A antibody; PBP antibody; Peroxisome proliferator-activated receptor-binding protein antibody; PPAR binding protein antibody; PPAR-binding protein antibody; PPARBP antibody; PPARGBP antibody; RB18A antibody; Thyroid hormone receptor-associated protein complex 220 kDa component antibody; Thyroid receptor-interacting protein 2 antibody; TR-interacting protein 2 antibody; Trap220 antibody; TRIP-2 antibody; TRIP2 antibody; Vitamin D receptor-interacting protein complex component DRIP205 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15648

Immunogen:Peptide sequence around phosphorylation site of Threonine 1457(A-Y-T(p)-P-Q) derived from Human PPAR-BP.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MED1

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Metabolism