Phospho-MAP3K7 (Thr187) Polyclonal Antibody

SKU: E-AB-21065

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: Tak1 (phospho Thr187)

Target Synonym: M3K7;MAP3K 7;Map3k7;MEKK7;Mitogen activated protein kinase kinase kinase 7;Mitogen-activated protein kinase kinase kinase 7;TAK1;TGF beta activated kinase 1;TGF-beta-activated kinase 1;TGF1a;Transforming growth factor beta activated kinase 1;Transforming growth factor-beta-activated kinase 1

Research Areas: Cancer;Cardiovascular;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O43318

Accession:

Background: Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300

Calculated MW: 67kDa

ObservedMW: 60kDa