Phospho-HNF4A (Ser304) Antibody - Cat. #: CSB-PA443636

SKU: CSB-PA443636

Size :100ul

Clone Number:

Aliases:FLJ39654 antibody; FRTS4 antibody; Hepatic nuclear factor 4 alpha antibody; Hepatocyte nuclear factor 4 alpha antibody; Hepatocyte nuclear factor 4 antibody; Hepatocyte nuclear factor 4-alpha antibody; HNF 4 alpha antibody; HNF 4 antibody; HNF-4-alpha antibody; HNF4 antibody; HNF4A antibody; HNF4A_HUMAN antibody; HNF4a7 antibody; HNF4a8 antibody; HNF4a9 antibody; Hnf4alpha antibody; HNF4alpha10/11/12 antibody; MODY 1 antibody; MODY antibody; MODY1 antibody; NR2A1 antibody; NR2A21 antibody; Nuclear receptor subfamily 2 group A member 1 antibody; OTTHUMP00000031060 antibody; OTTHUMP00000031062 antibody; TCF 14 antibody; TCF antibody; TCF-14 antibody; TCF14 antibody; Tcf4 antibody; Transcription factor 14, hepatic nuclear factor antibody; Transcription factor 14 antibody; Transcription factor HNF 4 antibody; Transcription factor HNF-4 antibody; Transcription factor HNF4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P41235

Immunogen:Peptide sequence around phosphorylation site of serine 304 (L-R-S(p)-Q-V)derived from Human HNF4a.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes,including hepatocyte nuclear factor 1 a, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.

Kritis A.A,et al.Gene 173:275-280(1996)
Drewes T,et al.Mol. Cell. Biol. 16:925-931(1996)
Yamagata K,et al.Nature 384:458-460(1996)
Tanaka T,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HNF4A

Research Areas:Epigenetics and Nuclear Signaling;Cancer?Cardiovascular;Developmental biology;Metabolism;Signal transduction