Phospho-HDAC5 (Ser498) Polyclonal Antibody

SKU: E-AB-20888

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: HDAC5 (phospho Ser498)

Target Synonym: Antigen NY CO 9;Antigen NY-CO-9;HD5;HDAC 5;HDAC5;HDAC5;Histone deacetylase 5;NY CO 9

Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UQL6

Accession:

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 122kDa

ObservedMW: 122kDa