Phospho-CDC25A (Ser178) Antibody - Cat. #: CSB-PA065947

SKU: CSB-PA065947

Size :100ul

Clone Number:

Aliases:Cdc 25a antibody; CDC25A antibody; CDC25A2 antibody; CDC25A2 CAG isoform antibody; Cell division cycle 25 homolog A (S. pombe) antibody; Cell division cycle 25A antibody; Cell division cycle 25A isoform a antibody; Cell division cycle 25A isoform b antibody; D9Ertd393e antibody; Dual specificity phosphatase Cdc25A antibody; M phase inducer phosphatase 1 antibody; M-phase inducer phosphatase 1 antibody; MGC115549 antibody; MPIP1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P30304

Immunogen:Peptide sequence around phosphorylation site of serine 178(Q-N-S(p)-A-P) derived from Human CDC25A .

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

Chen MS, Ryan CE, Piwnica-Worms H (2003)Mol Cell Biol 23, 7488-97
Hassepass I, Voit R, Hoffmann I (2003) J Biol Chem 278, 29824-9
S?rensen CS, et al. (2003) Cancer Cell 3, 247-58

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CDC25A

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology