Phospho-Akt(Ser473) antibody , Cat. # FNab06402

SKU: FNab06402

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:5H4

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification.

Immunogen:v-akt murine thymoma viral oncogene homolog 1

Synonyms:AKT, AKT1, AKT1-phospho-S473, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha

Observed MW:60KD

Uniprot ID:P31749

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, WB

Recommended dilution:WB: 1:1000-1:4000; IHC: 1:50-1:200

Gene ID:

Research Area:Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Stem Cells