PHB Monoclonal Antibody

SKU: BT-MCA3263

Size:100μL

Background:Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

Research_area:Epigenetics and nuclear signaling, Cell biology, Cancer, Metabolism, Tags &amp, cell markers

Target_protein:PHB

applications:WB, IHC, ICC, FCM

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Monoclonal

Clone ID:5H7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PHB

Immunogen:Purified recombinant fragment of human PHB expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):30kDa

UniProt accession:P35232

Synonyms:PHB1

GeneID:5245