PGC-1alpha Monoclonal Antibody

SKU: BT-MCA4827

Size:100μL

Background:The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Research_area:Others

Target_protein:PGC-1alpha

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:1G8

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:PGC-1alpha

Immunogen:Purified recombinant fragment of human PGC-1alpha expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):91kDa

UniProt accession:Q9UBK2

Synonyms:PPARGC1A, LEM6, PGC1, PGC1A, PGC-1v, PPARGC1, PGC-1(alpha)

GeneID:10891