PFN2 Antibody - Cat. #: CSB-PA023267

SKU: CSB-PA023267

Size :50ul

Clone Number:

Aliases:D3S1319E antibody; PFL antibody; PFN 2 antibody; Pfn2 antibody; PROF2_HUMAN antibody; Profilin II antibody; Profilin-2 antibody; Profilin2 antibody; ProfilinII antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35080

Immunogen:Synthetic peptide of Human PFN2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Background:The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PFN2

Research Areas:Tags & Cell Markers;Signal transduction