GeneBio Systems
PER1 Polyclonal Antibody
PER1 Polyclonal Antibody
SKU:E-AB-62160
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:PER1
Target Synonym:PER1;PER;RIGUI;hPER
Research Areas:Epigenetics and Nuclear Signaling;Neuroscience
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse;Rat
Application:IHC;IF
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:O15534
Accession:
Background:This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Concentration:1mg/mL
Immunogen:Recombinant fusion protein of human PER1 (NP_002607.2).
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification method:Affinity purification
Dilution:IHC 1:50-1:100;IF 1:50-1:200
Calculated MW:
ObservedMW:
