Pepsinogen C/PGC Monoclonal Antibody

SKU: AN200124P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:PGC

Target Synonym:PGC;PEPC;PGII;gastricsin;Pepsinogen C;Pepsinogen II;PGC p

Research Areas:Signal Transduction;Cancer;Microbiology;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:IHC-P

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:6F7

UNIProt ID:P20142

Accession:

Background:Pepsiongen II is a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself. Among endoscopy clinic patients, PGII is a sensitive marker for extension of nonatrophic gastritis toward the corpus. PGI is a stable biomarker in assessment of fundic atrophy and has similar accuracy to PGI/PGII ratio among populations with prevalent nonatrophic pangastritis. Research also showed that decreased PG I level and PG I/II ratio are risk factors for gastric cancer. Combined use of serum PG I level and PG I/II ratio may help the early diagnosis of gastric cancer.

Concentration:1 mg/mL

Immunogen:Recombinant Human Pepsinogen C / PGC protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:50-1:200;

Calculated MW:

ObservedMW: