PEG10 Antibody - Cat. #: CSB-PA982049

SKU: CSB-PA982049

Size :50ul

Clone Number:

Aliases:AA407948 antibody; Edr antibody; Embryonal carcinoma differentiation regulated antibody; Embryonal carcinoma differentiation-regulated protein antibody; HB 1 antibody; HB1 antibody; KIAA1051 antibody; Mammalian retrotransposon-derived protein 2 antibody; Mar2 antibody; Mart2 antibody; MEF3 like 1 antibody; MEF3-like protein 1 antibody; MEF3L antibody; MEF3L1 antibody; MyEF 3 antibody; Myelin expression factor 3-like protein 1 antibody; Paternally expressed 10 antibody; Paternally expressed gene 10 ORF1 antibody; Paternally expressed gene 10 protein antibody; Peg10 antibody; PEG10 protein antibody; PEG10_HUMAN antibody; Putative uncharacterized protein PEG10 antibody; Retrotransposon gag domain containing 3 antibody; Retrotransposon gag domain-containing protein 3 antibody; Retrotransposon-derived gag-like polyprotein antibody; Retrotransposon-derived protein PEG10 antibody; RGAG3 antibody; Ty3/Gypsy-like protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q86TG7

Immunogen:Fusion protein of Human PEG10

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; ELISA:1:1000-1:5000, WB:1:200-1:1000

Background:This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PEG10

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Stem cells