PDZK1 Antibody, Biotin conjugated - Cat. #: CSB-PA722565HD01HU

SKU: CSB-PA722565HD01HU

Size :50ug

Clone Number:

Aliases:1700023D20Rik antibody; 2610507N21Rik antibody; 4921513F16Rik antibody; AI267131 antibody; AI314638 antibody; AL022680 antibody; C terminal linking and modulating protein antibody; CAP70 antibody; CFTR associated protein of 70 kDa antibody; CFTR associated protein; 70-KD antibody; CFTR-associated protein of 70 kDa antibody; CLAMP antibody; D3Ertd537e antibody; Dietary Pi-regulated RNA-1 antibody; Diphor-1 antibody; mPDZK1 antibody; Na(+)/H(+) exchange regulatory cofactor NHE-RF3 antibody; Na(+)/H(+) exchanger regulatory factor 3 antibody; Na/Pi cotransporter C-terminal-associated protein 1 antibody; Na/Pi cotransporter C-terminal-associated protein antibody; NaPi Cap1 antibody; NaPi-Cap1 antibody; NaPiCap1 antibody; NHERF 3 antibody; NHERF-3 antibody; NHERF3 antibody; NHRF3_HUMAN antibody; OTTHUMP00000015572 antibody; PDZ domain containing 1 antibody; PDZ domain containing protein 1 antibody; PDZ domain-containing protein 1 antibody; PDZD1 antibody; PDZK1 antibody; Sodium hydrogen exchanger regulatory factor 3 antibody; Sodium-hydrogen exchanger regulatory factor 3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q5T2W1

Immunogen:Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF3 protein (1-519AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PDZK1

Research Areas:Cancer; Metabolism; Signal transduction